Helping The others Realize The Advantages Of ceesdekker.net
Helping The others Realize The Advantages Of ceesdekker.net
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Applying solitary-molecule optical and AFM imaging and power-spectroscopy methods, we seek to unravel the mechanistic elements of the composition and dynamics of chromosomes. Our exploration passions consist of:
But how do morality, the dignity in the human being, my working experience with the that means of existence, follow within the motion of atoms? A purely naturalistic viewpoint fails here; a Christian point of view, I believe, is a much more sensible method to interpret these components of actuality.’
Multicolor imaging of your bacterial nucleoid and cell division proteins with blue, orange, and in the vicinity of-infrared fluorescent proteins
Our operate was promptly adopted up by Some others, most notably by Phaedon Avouris and colleagues at IBM, who in Oct 1998 released their results on transistors constructed from solitary- and multi-walled carbon nanotubes in Utilized Physics Letters.
This yielded a breakthrough. In only a few months, we ended up in a position to evaluate transport by an individual solitary-walled carbon nanotube. According to very low-temperature experiments by a brilliant PhD scholar in my group, Sander Tans (now a valued colleague and professor at Delft University of Technological know-how using an Lively analysis lab at AMOLF in Amsterdam), we showed that carbon nanotubes have been legitimate quantum wires with really long (micrometres) electronic coherence lengths — confirming theoretical predictions of metallic conduct.
Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of only one wire bridging two electrodes
‘Initially we checked out Organic systems using a Actual physical view and acted on the basis on the tools we knew. It took https://www.ceesdekker.net a couple of years in advance of we started Operating far more on the massive Organic problems. I then started to phone it nanobiology, a expression that didn't exist at some time.
2011, very first in vitro measurements of transport across a single biomimetic nuclear pore complex; development of multiplexed magnetic tweezers for kilo-molecule experiments; and fixed the system of homology recognition in DNA homologous recombination
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Pretty great, but that wasn’t seriously where my fascination lay. I needed to pioneer and I had the sensation which was no longer attainable, as the most fascinating basic insights experienced already been uncovered. But my area had produced many remarkable new tools to evaluate individual molecules. I decided that I planned to utilize this to biology, to look at it from a physical perspective.’
FtsZ treadmilling is essential for Z-ring condensation and septal constriction initiation in bacterial cell division
Later on we spoke again briefly due to the fact Dekker felt that our dialogue of his religion quickly became purely philosophical, While Furthermore, it concretely allows him in his work.
Developments in nanotechnology while in the nineties designed making Digital equipment from one molecules a risk. Cees Dekker recounts how his workforce established a home-temperature transistor based on a single carbon nanotube.
Supercoiling-dependent DNA binding: quantitative modeling and programs to bulk and single-molecule experiments